Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 324
Gene Symbol: APC
APC 		0.600 Biomarker group RGD Enhanced colitis-associated colon carcinogenesis in a novel Apc mutant rat. 19694754 2009
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		0.600 Biomarker group RGD Diclofenac, a selective COX-2 inhibitor, inhibits DMH-induced colon tumorigenesis through suppression of MCP-1, MIP-1α and VEGF. 21268133 2011
Entrez Id: 596
Gene Symbol: BCL2
BCL2 		0.560 Biomarker group RGD These findings suggest an indirect pathway for Bcl-2 over-expression in PhIP-induced colon tumors involving beta-catenin, c-Myc and E2F1. 17404573 2007
Entrez Id: 4318
Gene Symbol: MMP9
MMP9 		0.540 Biomarker group RGD Diclofenac, a selective COX-2 inhibitor, inhibits DMH-induced colon tumorigenesis through suppression of MCP-1, MIP-1α and VEGF. 21268133 2011
Entrez Id: 4318
Gene Symbol: MMP9
MMP9 		0.540 ModifyingMutation group RGD Identification of gene expression profiles correlated to tumor progression in a preclinical model of colon carcinogenesis. 20428773 2010
Entrez Id: 4609
Gene Symbol: MYC
MYC 		0.530 Therapeutic group RGD MicroRNA profiling of carcinogen-induced rat colon tumors and the influence of dietary spinach. 22641368 2012
Entrez Id: 1786
Gene Symbol: DNMT1
DNMT1 		0.520 Therapeutic group RGD Further, 5-azacytidine potentiated cisplatin induced antitumor activity by involving decreased expression of pAKT, DNMT1 and an increased expression of p38 in colon tumors. 19723570 2009
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		0.340 Biomarker group RGD In colon tumors relative to the mucosa, the protein and mRNA levels of c-myc were increased, while the levels of p16 and p27 were decreased. 12189186 2002
Entrez Id: 80781
Gene Symbol: COL18A1
COL18A1 		0.210 ModifyingMutation group RGD Effect of oral Lactococcus lactis containing endostatin on 1, 2-dimethylhydrazine-induced colon tumor in rats. 16437622 2005
Entrez Id: 3718
Gene Symbol: JAK3
JAK3 		0.200 Therapeutic group RGD Role of cytokines and Jak3/Stat3 signaling in the 1,2-dimethylhydrazine dihydrochloride-induced rat model of colon carcinogenesis: early target in the anticancer strategy. 23514809 2013
Entrez Id: 7498
Gene Symbol: XDH
XDH 		0.200 Biomarker group RGD Xanthine oxidase activity in intestinal tumors induced by 1,2-dimethylhydrazine dihydrochloride. 3163916 1988
Entrez Id: 898
Gene Symbol: CCNE1
CCNE1 		0.200 Biomarker group RGD Overexpression of cyclin D1 and cyclin E in 1,2-dimethylhydrazine dihydrochloride-induced rat colon carcinogenesis. 14614307 2000
Entrez Id: 4221
Gene Symbol: MEN1
MEN1 		0.200 ModifyingMutation group RGD Reduction of menin expression enhances cell proliferation and is tumorigenic in intestinal epithelial cells. 15054094 2004
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.500 Biomarker group HPO
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		0.340 Biomarker group HPO
Entrez Id: 3815
Gene Symbol: KIT
KIT 		0.140 Biomarker group HPO
Entrez Id: 4193
Gene Symbol: MDM2
MDM2 		0.120 Biomarker group HPO
Entrez Id: 657
Gene Symbol: BMPR1A
BMPR1A 		0.110 Biomarker group HPO
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		0.110 Biomarker group HPO
Entrez Id: 6390
Gene Symbol: SDHB
SDHB 		0.100 Biomarker group HPO
Entrez Id: 6389
Gene Symbol: SDHA
SDHA 		0.100 Biomarker group HPO
Entrez Id: 6391
Gene Symbol: SDHC
SDHC 		0.100 Biomarker group HPO
Entrez Id: 64218
Gene Symbol: SEMA4A
SEMA4A 		0.100 Biomarker group HPO
Entrez Id: 5156
Gene Symbol: PDGFRA
PDGFRA 		0.100 Biomarker group HPO
Entrez Id: 6794
Gene Symbol: STK11
STK11 		0.100 Biomarker group HPO